Quicksilver - Bully Maguire dance

Unlike Peter Parker, who's a sweet kid deep down (as long as you ignore his occasional bouts of destructive adolescent rage), the other, more Eastern European P(i)eter has always been a jerk. So it's unsurprising that the Symbiote Suit makes him completely obnoxious.

He's so obnoxious, conveniently, that villains will lose all self-control when they see his sweet post-emo shoegaze mumblecore-inspired dance moves, and will bash their own heads in against his faux Retaliate 2-5. Meanwhile, you can basic-defend and negate between 1 and 9 damage (depending on how many of the trillion upgrades you have out, and whether it was a Maximum Velocity turn) and then untap.

Between Taunt, Unflappable and Specialized Training you have adequate card draw by Protection standards. Change of Fortune is notable by its absence - you wouldn't believe how rarely it drew cards in testing. Minions that are puny enough to be killed consistently by retaliation effects generally don't do enough damage to trigger the Energy Barriers if you defend (once built up), and don't activate Electrostatic Armor if you don't. The minions you pull out with "Come Get Me, Bub!" generally take a point or two of retal, but are ultimately mashed by Quicksilver and friends getting their hands dirty.

Your thwarting is less than impressive until you have all your upgrades out, so in some match-ups you may even choose to forego Defense Specialist for Surveillance Specialist - two basic thwarts for four per turn (with Hyper Perception and Symbiote Suit) should be more than enough to cover your share, whether in solo or multi.

There's a handful of stuns in the deck between Mockingbird and Iron Fist, plus some extra damage mitigation in Northstar. These are there to make sure you never bleed out of control; alongside the always-popular Professor X in case you really really really need to flip down. Starhawk is just there to Be Efficient (TM), as one of Quicksilver's problems is that his individual cards don't make enough of an impact on the board state. I originally had a lower ally count, and the deck had a bad habit of just collapsing under pressure.

Speaking of flipping down, while you'll generally not get much use out of Superpowered Siblings in this deck (and effectively zero use out of Serval Industries), don't forget you get the extended Maximoff Mulligan (TM) on turn 1!

Your first-turn targets are Friction Resistance, Accelerated Reflex/Armored Vest, and Deft Focus, in that approximate order. Turn 1 Specialized Training isn't the worst play your could make, but it'll take you long enough to bring it online that it's better to mulligan away the side-scheme if you aren't already in position to play out at least one other of the above. Symbiote Suit can generally wait until your first complete cycle through the deck, but you will almost certainly need to play it the second time around.