Colossus gets tough

Colossus not tough enough? Let's make him tougher!

Armor, Polaris and Warpath are your tough allies. Hope Summers is there to recur any of Colossus' excellent superpower cards.

Warpath ability will let you play "Come Get Me, Bub!" in the villain phase if you're struggling for toughs; and Serve and Protect is occasionally going to come in clutch in stopping threat and getting some more toughs (which Warpath is needed for)!

Mutant Protectors is there to help with economy a bit - it does have 4 ally targets; though it is the most cuttable card from this deck if you wanted to add in 2 more Hard to Ignore or Powerful Punch.

Stepford Cuckoos is just an auto-include for X-Men decks. Treachery cancellation is so useful if you are able. Astonishing X-Men is a really good card for Colossus (and Shadowcat) - you're going to fully cancel 2 villain activations. Establish Perimeter is also great - potentially nullifying up to 4 villain activations in multiplayer. Once you're ahead of the villain in action counts; you're setting yourself up better to win.

He doesn't benefit from Deft Focus or X-Gene due to his low cost hero events and superpowers; so they were actually an easy cut.